Not that I really have the ability to answer this, but I'll give it a whirl.
The real question is: can a person believe that a divine or far-advanced being could create the Universe, knowing that it would eventually give rise to intelligent life, but stay "hands-off" in interfering with the course of that Universe or the life it contains? I think this is approximately what
@Deezer Shoove believes (
but he can speak for himself). In such a creation, it could lead to life which doesn't have souls, or at least in this thought experiment it is possible.
In other words, intelligent design doesn't necessarily lead to souls. The two can be mutually exclusive. In that line of thinking, Humans create artificial "realms" all the time and call them video games. Interject generative AI in those "games" and we might end up creating a universe that is completely soulless.