Insulin resistance condition is associated to the development of several syndromes, such as obesity, type 2 diabetes mellitus and metabolic syndrome.
Although the factors linking insulin resistance to these syndromes are not precisely defined yet, evidence suggests that the elevated plasma free fatty acid (FFA) level plays an important role in the development of skeletal muscle insulin resistance.
Accordantly, in vivo and in vitro exposure of skeletal muscle and myocytes to physiological concentrations of saturated fatty acids is associated with insulin resistance condition.
Several mechanisms have been postulated to account for fatty acids-induced muscle insulin resistance, including Randle cycle, oxidative stress, inflammation and mitochondrial dysfunction.
Here we reviewed experimental evidence supporting the involvement of each of these propositions in the development of skeletal muscle insulin resistance induced by saturated fatty acids and propose an integrative model placing mitochondrial dysfunction as an important and common factor to the other mechanisms.
This is what I recall from reading what a named Covert Bailey thought about the use of sugar and alcoholLowIQTrash » 10 May 2025, 8:52 am » wrote: ↑ (Hint: It’s not the apples and oranges, it’s the hot dogs and hamburgers)
https://lipidworld.biomedcentral.com/ar ... 511X-11-30
Idiots Pee Pee pants after learning this fact and DENY it![]()
LowIQTrash » 10 May 2025, 8:52 am » wrote: ↑ (Hint: It’s not the apples and oranges, it’s the hot dogs and hamburgers)
https://lipidworld.biomedcentral.com/ar ... 511X-11-30
Idiots Pee Pee pants after learning this fact and DENY it![]()
So that means, EVERYTHING in your article is PURE SPECULATION and has nothing DEFINITIVE to prove the claims!!Although the factors linking insulin resistance to these syndromes are not precisely defined yet....
I would wager that drinking a glass of orange juice in a single sitting - let's say inside of 20 minutes - does more to promote insulin resistance than eating three hotdogs smothered in rich, creamery butter.LowIQTrash » 10 May 2025, 8:52 am » wrote: ↑ (Hint: It’s not the apples and oranges, it’s the hot dogs and hamburgers)
https://lipidworld.biomedcentral.com/ar ... 511X-11-30
Idiots Pee Pee pants after learning this fact and DENY it![]()
I am trying to watch what I eat.LowIQTrash » 10 May 2025, 8:52 am » wrote: ↑ (Hint: It’s not the apples and oranges, it’s the hot dogs and hamburgers)
https://lipidworld.biomedcentral.com/ar ... 511X-11-30
Idiots Pee Pee pants after learning this fact and DENY it![]()
Why don't you open a grocery store down in Boogeytown, Africa USA....stock it with nothing but the healthiest fresh produce and then work the cash register..?JohnnyYou » 10 May 2025, 12:01 pm » wrote: ↑ I am trying to watch what I eat.
On
Yesterday's troll said our skeletons are 25000 calories. I replied "Good to know I'll never go hungry "
Yeah, fat, carbs, sugars, at least there is more than RFK Soylent Green to choose from.. At least at my grocery store.
Just getting good food varies by location.. Downtown has been bad for years in America. Poison for Profit!
One look at 70 year old Kennedy tells any sane person that he knows a thing or 2 about basic nutrition and healthy lifestyle habits.JohnnyYou » 10 May 2025, 12:01 pm » wrote: ↑ I am trying to watch what I eat.
On
Yesterday's troll said our skeletons are 25000 calories. I replied "Good to know I'll never go hungry "
Yeah, fat, carbs, sugars, at least there is more than RFK Soylent Green to choose from.. At least at my grocery store.
Just getting good food varies by location.. Downtown has been bad for years in America. Poison for Profit!
So love beating Nancy Reagan at that one..*GHETTOBLASTER » 10 May 2025, 12:27 pm » wrote: ↑ One look at 70 year old Kennedy tells any sane person that he knows a thing or 2 about basic nutrition and healthy lifestyle habits.
Now go have yourself another Saturday morning bong hit while you spend the entire day posting gay videos on the internet.
People have called me Jimmy Neutron*GHETTOBLASTER » 10 May 2025, 12:23 pm » wrote: ↑ Why don't you open a grocery store down in Boogeytown, Africa USA....stock it with nothing but the healthiest fresh produce and then work the cash register..?
Call your heath food store "THE HEALTH FOOD OASIS" and make a promise to your wonderfully vibrant Pet Negro Monkey Clientelle that you will not prosecute shoplifting just as long as the thief is a negro and if the amount is less than $1000....?
Show us how it's done...!
Lead by example you bat **** crazy White Guilt Space Cadet...!!!
So now you are comparing the bleak and lonely life you have been doomed to live, as a chronic, fried potato Stoner Dude .....
Get a medport installed.
Waste of money.
The left points at "Rachel" Levine and tells us that it is the epitome of health.*GHETTOBLASTER » 10 May 2025, 12:27 pm » wrote: ↑ One look at 70 year old Kennedy tells any sane person that he knows a thing or 2 about basic nutrition and healthy lifestyle habits.
Now go have yourself another Saturday morning bong hit while you spend the entire day posting gay videos on the internet.
They should all be removed.SouthernFried » 10 May 2025, 6:33 pm » wrote: ↑ The left points at "Rachel" Levine and tells us that it is the epitome of health.
Cannonpointer » 10 May 2025, 10:20 am » wrote: ↑ I would wager that drinking a glass of orange juice in a single sitting - let's say inside of 20 minutes - does more to promote insulin resistance than eating three hotdogs smothered in rich, creamery butter.
I'm not a dietorian, but I play one on the interweb.
I monitored my blood sugar using a blood sugar testing device, the same kind diabetics may use. It showed no discernible spikes in blood sugar throughout the trial whatsoever — absolutely none. In fact, my blood sugar remained incredibly steady throughout the trial.
My highest blood sugar reading of the trial was 94, which is still medium-low. All that sweet fruit in my diet simply did not have any adverse effect on my blood sugar.
Eating this way gave my blood sugar more consistency than ever. I couldn’t spike my blood sugar on this diet if I tried. Even eating 19 bananas in one day made no difference.AlkalizingI measured my urine pH several times on the last day of the trial, and all the readings were between 7.4 and 8.0, very much on the alkaline side. Testing urine is less accurate than testing blood, but I see no cause for concern that this diet would be acidifying.
One of the biggest health myths of this century (1925-2025) is that consuming sugar / carbs causes diabetes.*GHETTOBLASTER » 10 May 2025, 9:29 am » wrote: ↑ This is what I recall from reading what a named Covert Bailey thought about the use of sugar and alcohol
Alcohol and processed sugar are the tiniest food molecules and they are able to be absorbed before the other [larger] food molecules can dive into the receptor sites on the intestinal wall.
Food as it passes through the intestine is on a moving assembly line...so some of the good stuff passes through without being absorbed...because table sugar and alcohol took "cuts in line".
Good evening LIQT..LowIQTrash » 10 May 2025, 8:55 pm » wrote: ↑ One of the biggest health myths of this century (1925-2025) is that consuming sugar / carbs causes diabetes.
A keto diet is often prescribed as a “natural cure” (by excluding carbs from the diet) but it does not alleviate the elevated A1C levels in the long term. Your body still will be unable to accept carbs as insulin production and utilization are both compromised.
Someone who eats sweet potatoes, lentils, black beans, apples, mangoes, oranges, spinach, kale, etc. and cuts out fat completely (other than maybe 1 teaspoon of olive oil and half an avocado a day) will cure T2 diabetes after maybe 1 yr of disciplined diet.
My suggestion is unbelievable to the majority of the peons (who have been misled by the JWO speared medical industry) but this is the truth.
The type of diabetes I’m describing is self-inflicted. Of course, if someone suffers damage to the pancreas (from an infection, for example) they can develop something like Type 1.5 diabetes.*GHETTOBLASTER » 10 May 2025, 9:24 pm » wrote: ↑ The school of thought has always been ...
..Archeologists can see signs of diabetes in skeletal remains, especially when certain combos of indicators are present.
The word is diabetes was pretty rare back in Fred Flintstone's day.
We Man Apes spent most of our time as hominids adapted to a feast or famine existence.
Our systems didn't need to be as "ramped up" all the time trying to meet the demands of metabolizing such a constant supply of simple, processed sugars and alcohol.
Now this discovery about fat being a diabetes trigger is interesting.
Going back to the Ape Diet comparison....I think animal fat intake is a fairly rare treat for them.
****** closer to the lower primates in many ways.
They were taken right out of a Stone Age existence [and feast or famine diet] just 300 years ago.
They are more prone to getting diabetes than the more evolved races that sprang forth from the negro.
also......
Eskimos have eaten almost exclusively meat loaded with lots of fat for 1000s of years..so I'm really curious to know how predisposed they are to diabetes...?